The American public has become increasingly more aware of the importance of a healthy diet low in saturated fats and cholesterol. Scientific evidence establishes that diets high in saturated fats and cholesterol are associated with increased levels of total and LDL “bad” cholesterol; and thus with increased risk of coronary heart disease. Scientific evidence also demonstrates that diets low in saturated fats and cholesterol are further associated with lower total and LDL cholesterol levels.
The actual intake of saturated fats exceeds recommend levels in the diets of many people in the United States. It is important to consume less than 10 percent of calories from saturated fat, and an average of thirty percent or less of total calories from all fat. Total cholesterol intake should be less than 300mg daily.
Foods containing at least 0.65g per serving of plant sterol esters, eaten twice a day with meals for a total intake of at least 1.3g, as part of a diet low in saturated fat and cholesterol may reduce the risk of heart disease. A serving of Prexator supplies 2.0g of plant sterol esters.
Plant sterols are cholesterol-like molecules that are found naturally in plants. They are the plant’s version of cholesterol molecules and, thus, are collectively referred to a “Phytosterols”. Plant Stanols are also considered phytosterols, they differ from plant sterols because the double bond present between carbon 5 and 6 is reduced. The FDA finds conclusive evidence in support of both plant sterols and stanols in support of coronary heart disease, but only plant sterols esters in the form of dietary supplementation.
Plant sterols are commonly esterified. This is a process by which a fatty acid is biochemically linked to the hydroxyl functional group on the number 3 carbon of the sterol molecule. This then forms an ester bond; hence the term, “esterified”. Esterification serves to make the phytosterols more soluble and better dispersed in the gastrointestinal tract and incorporation into the mixed micelles.
Regarding mixed micelles, the following is an excerpt (pg. 76538) from the December 8, 2010 comprehensive FDA review of phytosterols and risk of coronary heart disease assessment:
“Intestinal absorption of cholesterol requires cholesterol be incorporated into mixed micelles of the intestinal digesta. Intestinal micelles form when dietary fatty acids, pancreatic juice, and bile salts come together at the same time in the small intestine. The process of eating food stimulates the secretion of pancreatic juice and of bile salts into the intestine. The presumptive primary site of phytosterol interaction with cholesterol is within the micelles, where phytosterols are thought to block the transfer of cholesterol from micelles to intestinal mucosal cells. This mechanism supports the theory that the effectiveness of dietary phytosterols in reducing blood cholesterol levels depends on the phytosterols being consumed concurrently with food and dietary fat to ensure maximal incorporation of phytosterols into intestinal micelles.”
Current scientific and clinical evidence indicates that plant sterol ester supplements are generally safe in conjunction with statin based medications; in many cases even more effective than doubling the statin dose.
Scimera BioScience has formulated Prexator to contain the optimal levels of plant sterol esters, while providing increased dietary supplemental intakes of Coenzyme Q 10 to maintain subcellular energy production. Current data suggests increased levels of Coenzyme Q 10 may benefit patients on statin based treatment. Prexator additionally contains appropriate levels of vitamins to complement overall health.
While the development of coronary heart disease depends on many factors such as: family history of coronary artery disease, elevated blood total and LDL cholesterol, excess body weight, hypertension, smoking, diabetes, and physical inactivity; Prexator may help to achieve optimal cholesterol levels. Available clinical data indicates statistically significant reductions in LDL/total cholesterol levels given an appropriate daily intake of phytosterols. An effect that may be additive to statin based LDL/total cholesterol reductions. Ask your physician today about adding Prexator to your daily regimen.
The better management of body weight, benefits of exercise, and appropriate management of these risk factors should be aggressively addressed with your health care provider to help lower the risk of coronary heart disease.
Take Prexator as directed two capsules twice daily with meals or as directed by physician and start taking charge of your health today!†